منابع مشابه
Age-related changes in rat retina.
PURPOSE To describe the changes in rat retina occurring with ageing by means of histological methods, scanning electron microscopic observations and morphometrical data; and to study by means of biochemical methods the amount of protein content in retinal tissues. METHODS Samples of fresh retinal tissue obtained from young, adult, and aged rats were studied by means of traditional histologica...
متن کاملModeling age-related changes in muscle-tendon dynamics during cyclical contractions in the rat gastrocnemius.
Efficient muscle-tendon performance during cyclical tasks is dependent on both active and passive mechanical tissue properties. Here we examine whether age-related changes in the properties of muscle-tendon units (MTUs) compromise their ability to do work and utilize elastic energy storage. We empirically quantified passive and active properties of the medial gastrocnemius muscle and material p...
متن کاملAge-related smooth muscle reactivity changes in the rat bladder: an in vitro study.
An experimental study was conducted to investigate developmental changes of the rat detrusor smooth muscle (DSM) reactivity from newborn to adult period. Urinary bladders were obtained from adult (4 months old), 1-month-old and newborn (4-7 days old) male Sprague-Dawley rats. DSM reactivity of the three groups was evaluated in organ chambers. The newborn DSM strips revealed markedly increased p...
متن کاملAge-related changes on the surface of vitreous collagen fibrils.
PURPOSE To determine whether aging vitreous collagen fibrils undergo ultrastructural changes that might underlie vitreous liquefaction and posterior vitreous detachment. METHODS Vitreous collagen fibrils from 21 human subjects (age range, 3-89 years) and from bovine eyes were isolated on electron microscopy grids. Cupromeronic blue labeling in the presence of 0.3 M MgCl(2) and immunogold labe...
متن کاملElectron paramagnetic resonance reveals age-related myosin structural changes in rat skeletal muscle fibers.
We tested the hypothesis that low specific tension (force/cross-sectional area) in skeletal muscle from aged animals results from structural changes in myosin that occur with aging. Permeabilized semimembranosus fibers from young adult and aged rats were spin labeled site specifically at myosin SH1 (Cys-707). Electron paramagnetic resonance (EPR) was then used to resolve and quantify the struct...
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ژورنال
عنوان ژورنال: Gerontology
سال: 1980
ISSN: 0304-324X,1423-0003
DOI: 10.1159/000212396